The Manifest Destiny was not part of the Great Depression. The Manifest Destiny was a concept in American history that expressed the belief that the United States was destined to expand its territory across the North American continent. The concept was popular in the 19th century and led to the acquisition of many territories, including Texas, California, and the Southwest. The Great Depression, on the other hand, was a global financial crisis that occurred in the 1930s and had devastating effects on the United States.