First voyage (1492-1493)
* Sailed from Palos de la Frontera, Spain, on August 3, 1492, with three ships: the Santa Maria, the Pinta, and the Nina.
* Reached the Bahamas on October 12, 1492, and landed on Guanahani (now known as San Salvador).
* Explored the islands of the Caribbean, including Cuba and Hispaniola (now Haiti and the Dominican Republic).
* Returned to Spain in 1493.
Second voyage (1493-1496)
* Sailed from Cadiz, Spain, on September 25, 1493, with 17 ships.
* Explored the Lesser Antilles, the Virgin Islands, and Puerto Rico.
* Founded the first Spanish colony in the Americas on the island of Hispaniola.
* Returned to Spain in 1496.
Third voyage (1498-1500)
* Sailed from Sanlúcar de Barrameda, Spain, on May 30, 1498, with six ships.
* Reached the coast of South America, near the Orinoco River.
* Explored the Gulf of Paria and the island of Trinidad.
* Returned to Spain in 1500.
Fourth voyage (1502-1504)
* Sailed from Cadiz, Spain, on May 11, 1502, with four ships.
* Explored the coast of Central America, including Honduras, Nicaragua, and Costa Rica.
* Reached the Isthmus of Panama.
* Returned to Spain in 1504.