Henry VIII was a large man, weighing over 300 pounds at the time of his death. He was also very active, enjoying hunting and other sports. This combination of factors put a strain on his heart and circulatory system. In addition, Henry VIII was a heavy drinker and ate a diet that was high in red meat and unhealthy fats. This contributed to his obesity and poor health.
Henry's health began to decline in the 1540s. He developed a number of health problems, including gout, diabetes, and kidney disease. In 1536, he suffered a serious leg injury when he fell from his horse. The wound became infected and never fully healed. This left Henry with a permanent limp and constant pain.
Henry died in the early hours of 28 January 1547 at Whitehall Palace. He was buried at St George's Chapel, Windsor Castle.